Proc. It is the most polyphyletic known enzyme: six distinct classes have been described, all catalyzing the same reaction but representing unrelated gene families with no known sequence or structural homology. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.

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This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). [Full Text: http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=10915626], Hess, K. C., Jones, B. H., Marquez, B., Chen, Y., Ord, T. S., Kamenetsky, M., Miyamoto, C., Zippin, J. H., Kopf, G. S., Suarez, S. S., Levin, L. R., Williams, C. J., Buck, J., Moss, S. B.

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Hess et al. medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions. Nat. The presence of this substitution in 1 or both alleles was associated with a 3.1-fold increase in estimated risk for stone formation and occurrence of the HCA phenotype. Adenylyl cyclase type 5 in cardiac disease, metabolism, and aging. Systems used to automatically annotate proteins with high accuracy: Select one of the options below to target your search: Select item(s) and click on "Add to basket" to create your own collection here (400 entries max),

Information which has been imported from another database using automatic procedures.

Mapping a gene defect in absorptive hypercalciuria to chromosome 1q23.3-q24. The algorithm is described in the ISO 3309 standard. (from NCBI), Buck, J., Sinclair, M. L., Schapal, L., Cann, M. J., Levin, L. R.

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It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.

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This subsection of the Names and taxonomy section is present for entries that are part of a proteome, i.e.

The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) American journal of physiology. information that you need at your fingertips. from the sequence. Some G proteins switch adenylyl cyclase on, increasing cAMP production, while others switch it off. Buck et al. The version number for both the entry and the canonical sequence are also displayed.

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This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (reviewed) or to the computer-annotated TrEMBL section (unreviewed).

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, The European Molecular Biology Laboratory, State Secretariat for Education, Research and Innovation, Guanylate cyclase domain-containing protein.



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